Verified February 2017 by Purdue University
Sponsor:
Collaborator:
USDA Beltsville Human Nutrition Research Center
Information provided by (Responsible Party):
Richard Mattes, Purdue University
ClinicalTrials.gov Identifier:
NCT03066713
First received: February 21, 2017
Last updated: February 23, 2017
Last verified: February 2017
Assess the impact of high antioxidant potato products on postprandial glycemic response and subsequent appetite and food intake.
| Glycemic Response Appetitive Behavior |
Other: Skin Off French Fry Other: Skin On French Fry Other: Hash brown Other: Carbohydrate control |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Intervention Model: Crossover Assignment Masking: No masking Primary Purpose: Basic Science |
| Official Title: | Post-prandial Glucose Response From Phytochemical Rich Potato Products |
- Appetite [ Time Frame: Every hour for 24 hours ]
Questionnaire on hunger, fullness, desire to eat, prospective consumption, thirst taken hourly on the same day as the feeding intervention
| Estimated Enrollment: | 24 |
| Actual Study Start Date: | January 31, 2017 |
| Estimated Study Completion Date: | May 25, 2017 |
| Estimated Primary Completion Date: | May 25, 2017 (Final data collection date for primary outcome measure) |
| Experimental: Experimental: A
Skin On French Fry – breakfast Skin On French Fry – lunch Mashed Potatoes – dinner |
Other: Skin On French Fry
Skin On French Fries will be provided at breakfast and lunch |
| Experimental: Experimental: B
Skin Off French Fry – breakfast Skin Off French Fry – lunch Mashed Potatoes – dinner |
Other: Skin Off French Fry
Skin Off French Fries will be provided at breakfast and lunch |
| Experimental: Experimental: C
Hash brown – breakfast Hash brown – lunch Mashed Potato – dinner |
Other: Hash brown
Hash brown potatoes will be provided at breakfast and lunch. |
| Experimental: Experimental: D
Pancake – breakfast Pretzels – lunch Macaroni – dinner |
Other: Carbohydrate control
A pancake will be provided at breakfast, and pretzels will be provided at lunch. |
Preliminary results from anthocyanin rich potato products suggest that a reduced postprandial glycemic response might be expected from certain types of potato products and that phenolic antioxidants may play a critical role in predicting the physiological response from potato products. Further, if consumed early in the day, such as at breakfast, a reduced glycemic response may serve to mitigate appetite and food consumption later in the day. Investigators aim to better understand how characteristics of commercial potato products (i.e. frozen potato products) with different phenolic profiles and content, may alter postprandial glycemic response and subsequent appetitive behavior. Specifically, investigators will assess the glycemic response from a serving of potato products in the morning using continuous glucose monitoring. Further, appetite and subsequent food consumption later in the day will be assessed through appetite logs and continuous glucose monitoring.
| Ages Eligible for Study: | 18 Years to 50 Years (Adult) |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- BMI 18.5-25, male or female
Exclusion Criteria:
- BMI outside 18.5-25
Please refer to this study by its ClinicalTrials.gov identifier: NCT03066713
| Purdue University | |
| West Lafayette, Indiana, United States, 47906 | |
| Contact: Richard Mattes, PhD 765-494-0662 mattes@nullpurdue.edu | |
Purdue University
USDA Beltsville Human Nutrition Research Center
| Principal Investigator: | Richard D Mattes, PhD | Purdue University |
| Responsible Party: | Richard Mattes, Principle Investigator, Purdue University |
| ClinicalTrials.gov Identifier: | NCT03066713 History of Changes |
| Other Study ID Numbers: | 055-046 |
| Study First Received: | February 21, 2017 |
| Last Updated: | February 23, 2017 |
| Individual Participant Data | |
| Plan to Share IPD: | Undecided |
| Studies a U.S. FDA-regulated Drug Product: | No | |
| Studies a U.S. FDA-regulated Device Product: | No | |
ClinicalTrials.gov processed this record on February 28, 2017